Table 2.
Estimates for outcomes changes per 5-year interval in year at surgery. Results are presented in terms of odds ratio for binary outcomes and coefficients for continuous outcomes.
| Outcome | Estimate | 95% CI | p value |
|---|---|---|---|
| 1 high risk factor at diagnosis | 1.11 | 0.98, 1.26 | 0.11 |
| 2 high risk factors at diagnosis | 0.90 | 0.79, 1.02 | 0.10 |
| 3 high risk factors at diagnosis | 0.98 | 0.73, 1.32 | 0.9 |
| PSA > 20 ng/ml | 0.64 | 0.57, 0.73 | <0.001 |
| Clinical stage cT3 | 0.90 | 0.80, 1.01 | 0.07 |
| Biopsy Gleason score ≥ 8 | 1.65 | 1.45, 1.88 | <0.001 |
| Pathologic stage ≥ pT3b | 0.82 | 0.73, 0.92 | 0.001 |
| Pathologic Gleason score ≥ 8 | 1.41 | 1.24, 1.60 | <0.001 |
| Positive surgical margins | 1.34 | 1.18, 1.52 | <0.001 |
| Lymph node invasion | 1.12 | 0.99, 1.26 | 0.08 |
| Number of nodes removed | 2.01 | 1.44, 2.58 | <0.001 |
| Number of positive nodes | 0.54 | 0.12, 0.96 | 0.01 |
| Specimen confined disease | 1.08 | 0.97, 1.22 | 0.17 |
| Adjuvant radiation therapy | 0.51 | 0.36, 0.73 | <0.001 |
| Adjuvant hormonal therapy | 0.24 | 0.15, 0.38 | <0.001 |