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. Author manuscript; available in PMC: 2017 May 1.
Published in final edited form as: BJU Int. 2015 Jun 10;117(5):740–747. doi: 10.1111/bju.13125

Table 3.

Multivariable Cox regression analysis assessing the relationship between year of surgery and oncologic outcomes (namely, biochemical recurrence, distant metastasis, and cancer specific mortality) in 1,033 high risk prostate cancer patients treated with radical prostatectomy and extended pelvic lymph node dissection between 1990 and 2013 at a single institution. Models were adjusted for age at surgery, pre-operative prostate specific antigen, pathologic stage (≤pT3a vs. ≥pT3b), lymph node invasion (no vs. yes), positive surgical margins (no vs. yes), and pathologic Gleason score (≤6 vs. 7 vs. ≥8).

Oncologic Outcomes HR 95% CI p value
Biochemical Recurrence 0.90 0.84, 0.96 0.01
Distant Metastasis 0.91 0.83, 0.99 0.039
Cancer Specific Mortality 0.97 0.88, 1.06 0.4

HR = hazard ratio per 5-year interval at surgery; CI = confidence interval.