Figure 3.

SCFAs and BSCFAs inhibit ISO-potentiated lipolysis in human adipocytes. Lipolysis was measured after 1 hour of stimulation without (BASAL) and with 30 nM isoproterenol (ISO) in the absence (CTRL) or presence of 3 and 10 mM of propionic acid (PA), butyric acid (BA), isobutyric acid (I-BA) or isovaleric acid (I-VA), as shown in A) for PA and BA and B) for I-BA and I-VA. The values are related to BASAL CTRL (condition without lipolytic agent and SCFA or BSCFAs). Mean ± SD (n = 3-4) were used and significance levels were accepted when *p < 0.05, **p < 0.01 and ***p < 0.001.