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. 2004 Aug 27;32(15):4585–4595. doi: 10.1093/nar/gkh800

Figure 1.

Figure 1

Representation of the HIV-2 ROD RNA constructs used in this study. (A) The landmark sequences with known functions for the first 561 nt of HIV-2 RNA are indicated by boxes. TAR, polyA signal, PBS, ψ, SL1 and SD represent the trans-activation region, the poly(A) signal domain, the primer binding site, the encapsidation signal, the stem–loop 1 and the major splice donor site, respectively. (B) RNAs used in this study. The closed boxes represent the three in vitro characterized dimerization elements, the 5′ end of the PBS, the palindromic sequence in the encapsidation signal ψ and the SL1. The open boxes represent the cores of the two elements forming the long distance interaction, 189–196 and 543–550 (19). The numbers to the right indicate the origin of the nucleotides located downstream of the SD. Sequences removed in spliced RNAs are indicated by dotted lines. (C) The 5′ LTR intron missing in the 1–561 genomic RNA is represented by dotted lines. The splice acceptor and donor sites shown here were originally described in HIV-2 Rev transcripts (23).