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Histologic overviews of three choroidal melanoma (hematoxylin-eosin, original magnification ×12.5), expression of Melan-A/MART-1, HMB45, and S100 (original magnification ×400) for tumors E-1268-94 (Mel270) (top), E-994-95 (Mel285) (middle), and 131-96 (Mel290) (bottom) (original magnification ×400). The morphology and immunophenotypic profile of the three tumors are consistent with choroidal melanoma. The aspect of the iris of 131-96 (lower left) is consistent with a nevus of Ota.
