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. 2016 Apr 25;127(26):3424–3430. doi: 10.1182/blood-2016-01-695551

Table 2.

HRs of cytogenetic and clinical markers for event-free, relapse-free, and overall survival in multivariate analysis

HR 95% CI P2)
NCK-7 positive (n = 61)
 EFS 1.69 1.04-2.76 .035
 RFS 2.26 1.15-4.48 .019
 OS 2.33 1.36-3.99 .002
Hyperdiploidy (n = 33)
 EFS 0.43 0.21-0.90 .026
 RFS 0.43 0.16-1.14 .090
 OS 0.44 0.20-1.01 .053
7p-abnormality (n = 13)
 EFS 1.06 0.41-2.73 .909
 RFS 1.35 0.39-4.70 .639
 OS 1.10 0.38-3.17 .860
Normal karyotype (n = 20)
 EFS 0.85 0.43-1.70 .651
 RFS 0.98 0.40-2.43 .966
 OS 0.97 0.47-2.01 .928
Sex (male, n = 70)
 EFS 1.32 0.86-2.23 .186
 RFS 1.14 0.60-2.16 .688
 OS 1.41 0.84-2.38 .193
Age <2 y (n = 97)
 EFS 0.71 0.43-1.15 .159
 RFS 0.57 0.30-1.10 .093
 OS 0.82 0.49-1.38 .453
WBC count >20.0 × 109/L (n = 38)
 EFS 1.32 0.80-2.20 .276
 RFS 1.67 0.86-3.25 .129
 OS 1.62 0.95-2.76 .079
HSCT (n = 63)
 EFS 1.14 0.61-2.11 .680
 RFS 0.95 0.47-1.92 .882
 OS 1.18 0.67-2.08 .575