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. 2016 Sep 20;72(1):115–127. doi: 10.1093/jac/dkw381

Table 1.

AMP-resistant S. aureus display cross-resistance to various AMPs

Strain no. Passaged with Approximate no. of generationsa MIC (mg/L)b
LL-37 WGH PR-39 CNY100HLc
DA28823 WT, no passage none 192 16 4 24
DA30560 no peptide 322 192 16 4 24
DA29677 LL-37 189 >512 64 4 48
DA29680 LL-37 189 >512 128 8 32
DA30557 WGH 322 >512 192 12 48
DA30559 WGH 322 >512 256 12 32
DA36424 LL-37 and WGH 210 >512 192 12 32
DA35920 PR-39 168 >512 128 8 32
DA37296 PR-39 168 >512 96 8 32

aCalculated based on number of generations achieved in MIEM without peptide.

bMIC was determined in MIEM using the broth microdilution method.

cCNY100HL is a modified AMP derived from the human C3 complement peptide CNY21.28