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. Author manuscript; available in PMC: 2016 Dec 16.
Published in final edited form as: Curr Opin Obstet Gynecol. 2016 Oct;28(5):413–419. doi: 10.1097/GCO.0000000000000313

FIGURE 4.

FIGURE 4

Immunofluorescent labeling of pan-macrophage marker CD68 (red), M1 pro-inflammatory marker CD86 (orange), M2 pro-remodeling macrophage marker CD206 (green), and DAPI (blue). (a) a mesh-tissue section from a patient presenting with an exposure and implanted with the AMS Perigee prolapse mesh for 93 months; (b) a mesh-tissue section from a patient presenting with pain and implanted with the Gynecare TVT Secur for 6 months; (c) control tissue from patients without graft implantation. A predominance of pro-inflammatory M1 macrophages surround mesh fibers (*) consistent with a prolonged immune response could be observed in both (a) and (b); however, this response is limited to the area immediately adjacent to mesh fibers. Control tissue contained few or no macrophages as compared to mesh patient tissue. Magnification 200× [16▪]. Adapted with permission from [16▪].