Table 1. Clinical criteria for hereditary diffuse gastric cancer (HDGC) defined by the International Gastric Cancer Linkage Consortium guidelines (IDGLC) ¹⁵.

1	Two or more GC cases regardless of age, at least 1 confirmed DGC, in first-degree and second-degree relatives
2	Isolated individual diagnosed with DGC at age < 40 from a low incidence population
3	Personal or family history of both DGC and LBC, with 1 case < 50 years at time of diagnosis