Fig. 4.

Potential future brain modeling capabilities. A simplified schematic representing human brain development timescale, indicating several milestones during embryonic development (green), which could be modeling in brain ogranoids in future, following certain technical improvements (dark purple, for details, please see main text) (for a more detailed timescale of milestones, please see (Silbereis et al., 2016)). The timescale also indicates the onset of a subset of neurodevelopmental and neurological diseases, which could be modeled (or partly already are) by using the brain organoid technique (petrol color).