Table 3.
Association between overall within-person change in uric acid with change in systolic or diastolic blood pressure when increasing sodium intake from low to high
| N | Change in SBP |
Change in DBP |
|||||||
|---|---|---|---|---|---|---|---|---|---|
| r | β | P | P-interaction | r | β | P | P-interaction | ||
| Overall | 103 | −0.14 | −1.4 | 0.15 | − | −0.05 | −0.3 | 0.63 | |
| Baseline hypertension | |||||||||
| No | 68 | −0.22 | −1.9 | 0.07 | 0.19 | −0.04 | −0.2 | 0.72 | 0.57 |
| Yes | 35 | 0.09 | 1.2 | 0.61 | 0.07 | 0.6 | 0.67 | ||
| Elevated SBP | |||||||||
| No | 74 | −0.22 | −1.9 | 0.06 | 0.07 | −0.07 | −0.4 | 0.56 | 0.21 |
| Yes | 29 | 0.18 | 2.5 | 0.35 | 0.19 | 1.6 | 0.32 | ||
| Elevated DBP | |||||||||
| No | 87 | −0.13 | −1.2 | 0.24 | 0.60 | −0.03 | −0.2 | 0.79 | 0.64 |
| Yes | 16 | −0.21 | −3.2 | 0.43 | −0.13 | −1.3 | 0.63 | ||
| Salt Sensitive (absolute)* | |||||||||
| No | 70 | −0.13 | −0.9 | 0.29 | 0.33 | 0.09 | 0.4 | 0.44 | 0.78 |
| Yes | 33 | 0.07 | 0.4 | 0.68 | 0.05 | 0.2 | 0.79 | ||
| Salt Sensitive (percent)* | |||||||||
| No | 66 | −0.11 | −0.7 | 0.39 | 0.49 | 0.11 | 0.5 | 0.39 | 0.78 |
| Yes | 37 | 0.04 | 0.2 | 0.84 | 0.05 | 0.2 | 0.75 | ||
| Hyperuricemia > 6 | |||||||||
| No | 79 | −0.14 | −1.4 | 0.23 | 0.99 | −0.06 | −0.40 | 0.62 | 0.87 |
| Yes | 24 | −0.16 | −1.4 | 0.46 | −0.03 | −0.1 | 0.90 | ||
Based an increase in MAP of >5 mm Hg during high versus low salt intake
**Based an increase in MAP of >5% during high versus low salt intake