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. 2016 Dec 22;1(21):e86654. doi: 10.1172/jci.insight.86654

Figure 4. ATG16L1 in STBs regulates resistance to infection.

Figure 4

(A) Western blot detection of autophagy proteins ATG16L1, ATG7, BECLIN-1 and LC3 in BeWo CTBs and STBs and quantification of ATG16L1 protein levels in CTBs and STBs. Mean values ± SEM of 3 independent experiments. (B) Western blot detection of ATG16L1 in STBs after exposure to control or ATG16L1-specific siRNA. (C) Quantification of bacterial load in STBs treated with control or ATG16L1-specific siRNA. The graph shows mean values ± SEM of 4 independent experiments. *P < 0.05, **P < 0.01 by Mann-Whitney U test.