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. 2016 Oct 20;204(4):1523–1539. doi: 10.1534/genetics.116.193474

Figure 5.

Figure 5

Redundancy results in bet-hedging that is robust to mutation. (A) Redundancy in the CRN implementing the DC switch maintains molecular switching when chemical species are deleted. Marked in red is the switching probability for initial conditions (20,30,30,20) before deletion (0), after the deletion of x (1), and after the deletion of x and y (2). Contour lines show initial conditions of equal switching behavior. (B) Redundancy in the CRN implementing the AM molecular switch. Switching is maintained if the species x, y and b are removed in any order. We omit the case where y is removed before x due to symmetry. (C) A molecular switch that can reduce to either AM or DC when specific reactions are inhibited.