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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Pflugers Arch. 2016 Oct 19;468(11-12):1957–1968. doi: 10.1007/s00424-016-1887-5

Figure 6. CPX decreases insulin release and attenuates the consequences of glucose-induced ER stress in islets.

Figure 6

a. Insulin release in wt islets following glucose stimulation at 17mM or 25mM, or 40 mM KCl and treated with CPX at 20μΜ for 30min and 60min respectively. *, P<0.01 vs. untreated. b. Expression of insulin, CHOP, GRP94 and BiP in wt islets treated with high glucose alone or in combination with CPX (in KRB). Actin levels were assessed as loading control. High glucose experiment was performed in triplicates. All values are expressed as average +/− SD.