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After first coming into contact with the SiNW, the cell membrane extends along the entire length of the SiNW, engulfing the particle. This results in either complete or partial encapsulation of the SiNW into a small vesicle. The SiNW is then transported to the perinuclear region for processing. Eventually, the particle, through a yet unknown process, is able to leave the lysosome and is released to the cytosol.
