Table 1. Number of transferred embryos, pups, PLN homozygous KO mice, and PLN wild type (WT) mice in five lots.
Lot | Injected zygotes | Transferred embryos (%)a | Pups (%)b | PLN homozygous KO (%)c | PLN WT (%)d |
---|---|---|---|---|---|
1st lot | 660 | 607 (92.0) | 119 (19.6) | 8 (6.7) | 52 (43.7) |
2nd lot | 701 | 649 (92.6) | 173 (26.7) | 8 (4.6) | 55 (31.8) |
3rd lot | 644 | 578 (89.8) | 87 (15.1) | 13 (14.9) | 38 (43.7) |
4th lot | 695 | 623 (89.6) | 109 (17.5) | 18 (16.5) | 34 (31.2) |
5th lot | 1351 | 1228 (90.9) | 180 (14.7) | 23 (12.8) | 82 (45.6) |
Values in parenthesis shows generation rate.
aTransferred embryos/Injected zygotes
bPups/Transferred embryos
cPLN homozygous KO/Pups
dPLN WT/Pups.