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. 2016 Dec 16;11(12):e0167793. doi: 10.1371/journal.pone.0167793

Fig 3. Dose-dependent effect of bixin, norbixin, lutein, zeaxanthin and crocetin on RPE cell survival after A2E-induced blue-light phototoxicity.

Fig 3

Molecules were tested as described in Fig 2A. The concentrations of the substances are in μM. The positive control (cont–A2E) represents cells treated with DMSO alone. The negative control (cont + A2E) represents cells treated with A2E, but not with substances. Bars represent mean +/- s.e.m. of five independent experiments with n = 4. ***p<0.001; ****p<0.0001 compared to cont + A2E (One-way ANOVA, Dunnett’s post test).