Table 3. Significant differentially expressed genes in schizophrenia compared to controls (FDR < 0.1) from use of edgeR.
| Gene | Protein name | log2FCa | p-valuea | FDRa |
|---|---|---|---|---|
| NR4A1 | Nuclear receptor subfamily 4, group A member 1 | -1.13 | 1 x 10−6 | 0.019 |
| KLF4 | Kruppel-like factor 4 | -0.99 | 6.49 x 10−6 | 0.062 |
| EIF2AP4 | Eukaryotic translation initiation factor 2A pseudogene 4 | 1.08 | 2.26 x 10−5 | <0.1 |
| RTN4R | Reticulon 4 receptor | -0.69 | 2.49 x 10−5 | <0.1 |
| COL5A3 | Collagen, type V, alpha 3 | -0.55 | 3.44 x 10−5 | <0.1 |
| ARRDC3 | Arrestin domain containing 3 | 0.64 | 3.52 x 10−5 | <0.1 |
| ADAMTS9-AS2 | ADAMTS9 antisense RNA 2 | 0.53 | 3.74 x 10−5 | <0.1 |
| GAREML/FAM59B | GRB2 associated, regulator of MAPK1-like | -0.47 | 4.52 x 10−5 | <0.1 |
| MMD2 | Monocyte to macrophage differentiation-associated 2 | -0.49 | 5.26 x 10−5 | <0.1 |
| DUSP1 | Dual specificity phosphatase 1 | -0.7 | 5.6 x 10−5 | <0.1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.67 | 6.98 x 10−5 | <0.1 |
| ALDH1L2 | Aldehyde dehydrogenase 1 family, member L2 | 0.37 | 7.82 x 10−5 | <0.1 |
| ZNF385A | Zinc finger protein 385A | -0.49 | 8.26 x 10−5 | <0.1 |
| ZNF610 | Zinc finger protein 610 | 0.4 | 8.71 x 10−5 | <0.1 |
| PAPOLB | Poly(A) polymerase beta (testis specific) | 0.89 | 8.98 x 10−5 | <0.1 |
| PPP1R3B | Protein phosphatase 1, regulatory subunit 3B | 0.66 | 8.99 x 10−5 | <0.1 |
| SNORD116-24 | Small nucleolar RNA, C/D box 116–24 | 0.64 | 9.02 x 10−5 | <0.1 |
| ALDH3A2 | Aldehyde dehydrogenase 3 family, member A2 | 0.3 | 9.64 x 10−5 | <0.1 |
| GABRE | Gamma-aminobutyric acid (GABA) A receptor, epsilon | 1.2 | 9.79 x 10−5 | <0.1 |
| GBAP1 | Glucosidase, beta, acid pseudogene 1 | -0.57 | 1 x 10−4 | <0.1 |
aCalculated in edgeR as described in Methods