Table 2. Univariate logistic regression analysis.

	Univariate analysis
Predictors for LNC ≥ 12	OR (95% CI)	P value
Preoperative variables
Age, year	0.98 (0.96–0.99)	0.008
Sex (Male v Female)	0.76 (0.51–1.11)	0.158
CEA (> 4.4 v ≤ 4.4)	0.67 (0.46–0.97)	0.035
CA19-9 (> 6.7 v ≤ 6.7)	0.59 (0.37–0.95)	0.029
CA50 (> 8.9 v ≤ 8.9)	1.45 (0.96–2.19)	0.077
CA72-4 (> 1.2 v ≤ 1.2)	1.46 (0.95–2.25)	0.087
Lymphocyte count (> 1.2 v ≤ 1.2)	0.61 (0.38–0.97)	0.037
White blood cell count (> 6.7 v ≤ 6.7)	1.30 (0.88–1.92)	0.191
Neutrophils (> 2.2 v ≤ 2.2)	0.36 (0.15–0.87)	0.023
Anemia (Yes v No)	0.47 (0.32–0.69)	< 0.001
Platelet (> 320 v ≤ 320)	4.44 (2.16–9.15)	< 0.001
Location (referent = Proximal colon)
Distal colon	0.42 (0.25–0.70)	0.001
Rectum	0.55 (0.35–0.88)	0.013
Diameter, cm	1.37 (1.21–1.55)	< 0.001
Surgery (Laparoscopy v Open)	0.68 (0.39–1.17)	0.166
Pathological variables
Pathologist (Senior v Junior)	0.79 (0.47–1.32)	0.372
Macroscopy (referent = Polypoid type)
Ulcerative + Infiltrating type	1.05 (0.72–1.54)	0.785
Differentiation (referent = G1+G2)
G3+G4	1.66 (1.04–2.65)	0.035
Histology (referent = Adenocarcinoma)
Poorly differentiated + Mucous + Signet ring	3.98 (1.76–9.00)	0.001
Lymphovascular invasion (Yes v No)	1.06 (0.73–1.53)	0.775
Perineural invasion (Yes v No)	0.80 (0.55–1.16)	0.239
Deposit (Yes v No)	0.27 (0.16–0.45)	< 0.001
pT stage (referent = T1)
T2	2.92 (1.27–6.73)	0.012
T3	3.58 (1.67–7.66)	0.001
T4	2.90 (1.33–6.31)	0.007
pN stage (referent = N0)
N1	0.85 (0.57–1.27)	0.424
N2	1.85 (0.95–3.58)	0.070
Metastasis (M1 v M0)	0.80 (0.37–1.74)	0.572

Abbreviations: LNC, lymph node count; CEA, carcinoembryonic antigen; OR, odds ratio; 95% CI, 95% confident interval.