Table 2. Univariate logistic regression analysis.
Univariate analysis | ||
---|---|---|
Predictors for LNC ≥ 12 | OR (95% CI) | P value |
Preoperative variables | ||
Age, year | 0.98 (0.96–0.99) | 0.008 |
Sex (Male v Female) | 0.76 (0.51–1.11) | 0.158 |
CEA (> 4.4 v ≤ 4.4) | 0.67 (0.46–0.97) | 0.035 |
CA19-9 (> 6.7 v ≤ 6.7) | 0.59 (0.37–0.95) | 0.029 |
CA50 (> 8.9 v ≤ 8.9) | 1.45 (0.96–2.19) | 0.077 |
CA72-4 (> 1.2 v ≤ 1.2) | 1.46 (0.95–2.25) | 0.087 |
Lymphocyte count (> 1.2 v ≤ 1.2) | 0.61 (0.38–0.97) | 0.037 |
White blood cell count (> 6.7 v ≤ 6.7) | 1.30 (0.88–1.92) | 0.191 |
Neutrophils (> 2.2 v ≤ 2.2) | 0.36 (0.15–0.87) | 0.023 |
Anemia (Yes v No) | 0.47 (0.32–0.69) | < 0.001 |
Platelet (> 320 v ≤ 320) | 4.44 (2.16–9.15) | < 0.001 |
Location (referent = Proximal colon) | ||
Distal colon | 0.42 (0.25–0.70) | 0.001 |
Rectum | 0.55 (0.35–0.88) | 0.013 |
Diameter, cm | 1.37 (1.21–1.55) | < 0.001 |
Surgery (Laparoscopy v Open) | 0.68 (0.39–1.17) | 0.166 |
Pathological variables | ||
Pathologist (Senior v Junior) | 0.79 (0.47–1.32) | 0.372 |
Macroscopy (referent = Polypoid type) | ||
Ulcerative + Infiltrating type | 1.05 (0.72–1.54) | 0.785 |
Differentiation (referent = G1+G2) | ||
G3+G4 | 1.66 (1.04–2.65) | 0.035 |
Histology (referent = Adenocarcinoma) | ||
Poorly differentiated + Mucous + Signet ring | 3.98 (1.76–9.00) | 0.001 |
Lymphovascular invasion (Yes v No) | 1.06 (0.73–1.53) | 0.775 |
Perineural invasion (Yes v No) | 0.80 (0.55–1.16) | 0.239 |
Deposit (Yes v No) | 0.27 (0.16–0.45) | < 0.001 |
pT stage (referent = T1) | ||
T2 | 2.92 (1.27–6.73) | 0.012 |
T3 | 3.58 (1.67–7.66) | 0.001 |
T4 | 2.90 (1.33–6.31) | 0.007 |
pN stage (referent = N0) | ||
N1 | 0.85 (0.57–1.27) | 0.424 |
N2 | 1.85 (0.95–3.58) | 0.070 |
Metastasis (M1 v M0) | 0.80 (0.37–1.74) | 0.572 |
Abbreviations: LNC, lymph node count; CEA, carcinoembryonic antigen; OR, odds ratio; 95% CI, 95% confident interval.