Schematic representation of the increasing “levels of response” outlines by National Comprehensive Cancer Network Response Criteria for CML [27]
CBC, complete blood count; Ph, Philadelphia chromosome; qRT-PCR, quantitative reverse transcription polymerase chain reaction.
a For cytogenetic response, ≥20 metaphases must be studied.
b Major cytogenetic response includes partial and complete responses.
c Per the National Comprehensive Cancer Network, complete molecular remission requires a sample where a ≥4.5-log depletion can be assessed.