Extended Data Table 3. List of hox13 mutant sequences.

Frame shift mutation alleles that were used for each experiment are listed. The top sequence in each column show wild-type with gRNA sequence in red. Green is insertional, blue is substitutional mutations. a. hoxa13b mutation patterns. Sequence flanked by two gRNAs are abbreviated by black horizontal bars. c. hoxd13a mutation patterns. Sequence flanked by two gRNAs are abbreviated by black horizontal bars. d-f, Mutational patterns in triple knockout (mosaic for hoxa13b and hoxd13a) fish that is shown in Figure 3p-r are listed. Sequence flanked by two gRNAs are abbreviated by horizontal bars in e and f. Each hox13 gene shows some different mutations indicating that this fish is highly mosaic. The percentage of mutant alleles were calculated from the result of deep sequencing (Figure 3, Extended Data Table 4). g. Summary of genotype in all experiments. del. (deletion) and ins. (insertion)