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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Nature. 2016 Aug 24;537(7618):117–121. doi: 10.1038/nature19102

Extended Data Figure 7. Comparison of dihydropyridine binding site in CaVAb and CaV1.2.

Extended Data Figure 7

The pore domain of CaVAb is illustrated with two subunits in view, one in tan corresponding to domain III of CaV1.2 and one in blue corresponding to domain IV of CaV1.2. The amino acid residues in CaVAb corresponding to those that are important for dihydropyridine binding to CaV1.2 channels are highlighted in red. Bound amlodipine is illustrated with green sticks.