Fig. 3. Fusion of vaccinia virus mature virions with cells visualized by transmission electron microscopy.
Immunogold staining with antibody to the D8 membrane protein was performed prior to embedding and cryosectioning. (A) Fusion at the plasma membrane 10 min after infection. Arrow points to virus core. (B) Fusion with endosomal membrane 20 min after infection. Arrow points to junction of viral and endosomal membrane.
Modified from: Townsley, A.C., et al. (2006). J. Virol. 80, 8899–8908.