Table 2:
Means, number of subjects from whom the data was derived (in parentheses), and P values (from unequal variance t tests) of the absolute NAA, Cr, Cho, and mIns hippocampal GM concentrations and the volumes of the bilateral hippocampi in controls and patientsa
| Metabolite | Controls | Patients | P Value |
|---|---|---|---|
| NAA (mM) | 8.7 ± 1.2 (n = 11) | 8.8 ± 1.6 (n = 16) | .876 |
| Cr (mM) | 7.4 ± 1.2 (n = 10)b | 8.7 ± 2.2 (n = 19)b | .035b |
| Cho (mM) | 2.1 ± 0.3 (n = 10) | 2.3 ± 0.7 (n = 18) | .189 |
| mIns (mM) | 5.2 ± 0.9 (n = 10) | 6.1 ± 1.5 (n = 12) | .161 |
| Volume (cm3) | 8.4 ± 0.5 (n = 11)b | 7.5 ± 0.9 (n = 19)b | .003b |
a
Note the elevation of Cr and the reduction in volume in patients compared with controls.
b
Significant difference.