Figure 1. Desensitized kainate receptor at 3.8 Å resolution.
a, b, Cryo-EM density map (a) and atomic model (b) of 2S,4R-4-methylglutamate bound GluK2EM with each chain colored uniquely. Panel (a) has features shown from two map contours. c, Side and top view of the ATD tetramer, with cartoon highlighting 2-fold symmetry in the ATD layer. d, Top view of LBD tetramer with cartoon illustrating apparent 4-fold symmetry of the LBD layer when seen down the receptor central axis. e, Top view of the TMD with cartoon indicating domain symmetry.