Figure 2.
Sequences and modifications used in this study. (A) 1-ER and derivatives incorporated at position 21 (X) or 20 (Y) of the guide strand of an siRNA targeting PIK3CB. (B) PIK3CB on target sequence and two known off target sequences (YY1 and FADD). Red color indicates position of mismatches and lower case p indicates 5′ phosphate.