Figure 3.
Comparison of dissociation constants (KD) measured for human Ago2 PAZ domain binding to modified siRNAs using a fluorescence polarization assay. ER = 1-ER modification, T-I = triazole I, T-II = triazole II, structures shown in Figure 2.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.