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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Pain. 2017 Jan;158(1):48–57. doi: 10.1097/j.pain.0000000000000708

Table 2.

Significant clusters identified in an omnibus test for two 2×2 repeated measures ANOVA using group (CLBP > HC) and condition (Sadness > Baseline; Happiness > Baseline) as factors. These clusters were shown to have altered fcMRI with key hubs of the DMN (i.e., MPFC and PCC) following mood inductions.

Model Hemisphere Cluster Coordinates Cluster Size F(1, 31) Cluster p-val (<.05 FDR) Cluster Regions Voxels per Region
CLBP > HC, sadness > baseline Left −44 −28 20 453 11.59 .000 Parietal Operculum 169
Postcentral Gyrus 86
Supramarginal Gyrus 33
Planum Temporale 20
Heschl’s Gyrus 6
Right 58 −18 26 363 14.69 .000 Parietal Operculum 117
Supramarginal Gyrus 127
Postcentral Gyrus 76
Planum Temporale 23
Left −30 2 −4 315 15.64 .000 Posterior Insula 124
Putamen 74
Heschl’s Gyrus 39
Central Opercular Cortex 21
Planum Polare 10
Midline 4 28 24 128 12.36 .05 ACC 128
Left −38 −42 −36 125 8.77 .05 Cerebellum 67
Fusiform Gyrus 25
Inferior Temporal Gyrus 24
Left −24 52 34 124 13.17 .05 Frontal Pole 124
Right 34 4 0 119 12.55 .05 Posterior Insula 50
Putamen 15

CLBP > HC, happiness > baseline Right 28 −82 −40 208 24.18 .013 Cerebellum 208