Table 2.
CT findings and radiographic patterns of PD-1 pneumonitis
| Pt | Extent | Distribution | Lobar involvement | Specific CT findings | Radiographic pattern | ||
|---|---|---|---|---|---|---|---|
| Upper | Middle | Lower | |||||
| 1 | 5–25% | 5–25% | 25–50% | Peripheral and lower | All lobes | GGOs, reticular opacities, consolidations | NSIP |
| 2 | >50% | >50% | >50% | Diffuse | All lobes | GGOs, reticular opacities, consolidations, traction BE, centrilobular nodularity | AIP/ARDS |
| 3 | 25–50% | >50% | >50% | Diffuse | All lobes | GGOs, reticular opacities, consolidations, traction BE | AIP/ARDS |
| 4 | None | <5% | 5–25% | Mixed and lower | RLL | GGOs, reticular opacities | NSIP |
| 5 | 5–25% | 25–50% | >50% | Peripheral and lower | All lobes | GGOs, reticular opacities, consolidations | COP |
| 6 | 5–25% | 5–25% | 5–25% | Mixed and multifocal | LUL, lingual, LLL | GGOs, reticular opacities, consolidations, | COP |
| 7 | 5–25% | 5–25% | <5% | Mixed and multifocal | All lobes | GGOs, reticular opacities | COP |
| 8 | >50% | 25–50% | 25–50% | Diffuse | All lobes | GGOs, reticular opacities | HP |
| 9 | 5–25% | 5–25% | 25–50% | Peripheral and lower | All lobes | GGOs, reticular opacities, consolidations | COP |
| 10 | <5% | 5–25% | 25–50% | Peripheral and lower | All lobes | GGOs, reticular opacities, consolidations | NSIP |
| 11 | 25–50% | 25–50% | >50% | Mixed and multifocal | All lobes | GGOs, reticular opacities, | COP |
| 12 | >50% | >50% | >50% | Diffuse | All lobes | GGOs, centrilobular nodularity | HP |
| 13 | >50% | >50% | 25–50% | Mixed and upper | All lobes | GGOs, reticular opacities, | COP |
| 14 | 25–50% | 25–50% | >50% | Mixed and multifocal | All lobes | GGOs, reticular opacities, | COP |
| 15 | 25–50% | 25–50% | 25–50% | Peripheral and multifocal | All lobes | GGOs, reticular opacities, consolidations | COP |
| 16 | 5–25% | 5–25% | 25–50% | Mixed and multifocal | All lobes | GGOs, reticular opacities, consolidations | COP |
| 17 | <5% | <5% | 5–25% | Mixed and lower | RLL, LLL | GGOs, reticular opacities, consolidations | COP |
| 18 | 5–25% | 5–25% | >50% | Mixed and multifocal | All lobes | GGOs, reticular opacities, consolidations | COP |
| 19 | None | 5–25% | 5–25% | Mixed and multifocal | LLL | GGOs, reticular opacities, consolidations | COP |
| 20 | 5–25% | 25–50% | 25–50% | Mixed and multifocal | RUL, RML, LLL | GGOs, reticular opacities, centrilobular nodularity | COP |
GGO: ground-glass opacities
NSIP: non-specific interstitial pneumonia
AIP/ARDS: acute interstitial pneumonia/acute respiratory distress syndrome
COP: cryptogenic organizing pneumonia
HP: hypersensitivity pneumonitis
RUL: right upper lobe
RLL: right lower lobe
LUL: left upper lobe
LLL: left lower lobe