Table 2.
GERD Symptom Frequency | Incident Cases of Hearing Loss | Person-Years | Age-Adjusted RR | 95% CI | Multivariable-Adjusted RR* | 95% CI |
---|---|---|---|---|---|---|
No GERD | 6,027 | 239,198 | 1.00 | Reference | 1.00 | Reference |
Less than once/month | 1,090 | 38,832 | 1.12 | 1.05, 1.19 | 1.04 | 0.97, 1.11 |
Once/month | 559 | 17,684 | 1.26 | 1.15, 1.37 | 1.16 | 1.06, 1.26 |
Once/week | 928 | 31,140 | 1.19 | 1.11, 1.27 | 1.08 | 1.00, 1.16 |
Several times/week | 922 | 27,133 | 1.35 | 1.26, 1.45 | 1.17 | 1.09, 1.25 |
Daily | 316 | 7,885 | 1.59 | 1.42, 1.78 | 1.33 | 1.19, 1.49 |
P for trend (multivariable-adjusted) <0.001
RR denotes relative risk
Adjusted for age, race, body mass index, waist circumference, alcohol consumption, physical activity, nutrient (folate, vitamin A, vitamin B12, vitamin C, vitamin E, magnesium, potassium, beta-carotene, beta-cryptoxanthin, trans fat) intake, smoking status, hypertension, diabetes, tinnitus, thiazide use, furosemide use, and acetaminophen, aspirin, and ibuprofen use.