Skip to main content
. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Biol Psychiatry. 2016 Jun 16;81(7):606–615. doi: 10.1016/j.biopsych.2016.06.010

Figure 3.

Figure 3

Intra-CeA administration of the HCRT-R1 antagonist, SB-334867, reduces cocaine self-administration in long access rats under a fixed ratio (FR1) schedule of reinforcement. The bars represent mean number (+ SEM) of cocaine infusions during the first hour of a six-hour cocaine self-administration session. Administration of SB-334867 (0, 10, or 20 nmol SB) bilaterally into the CeA significantly decreases cocaine intake in LgA (n = 9) at the highest dose tested (20 nmol SB) versus vehicle (VEH). *p < 0.05 versus vehicle (VEH).