Stimulation of HCRT-R1 enhances GABAergic neurotransmission in the CeA of naïve but not short access (ShA) or long access (LgA) rats. A. Representative traces of sIPSCs in CeA neurons from naïve (left), ShA (middle), and LgA (right) before and during superfusion of the peptide ligand HCRT-1 (1 μM). B. Average change in sIPSC frequency (left) and sIPSC amplitude (right) in CeA neurons from naïve (n = 6), ShA (n = 6), and LgA (n = 6) rats following superfusion of HCRT-1. C. Average mIPSC frequency (left) and sIPSC amplitude (right) in CeA neurons from naïve (n = 8), ShA (n = 6), and LgA (n = 6) rats following superfusion of HCRT-1. *p < 0.05 by one-sample t-test, #p < 0.05 versus ShA and LgA.