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. Author manuscript; available in PMC: 2016 Dec 17.
Published in final edited form as: J Neurosci Res. 2009 Aug 1;87(10):2365–2374. doi: 10.1002/jnr.22046

Fig. 5.

Fig. 5

Upstream regulators of EPO in the retina and the RPE. Retinal cultures derived from rat or early passages of human RPE cells were exposed to 1% O2, 50% O2, or 5,000 lux light. Proteins were separated by SDS-PAGE and visualized by Western blot test. A: Increased expression of Hif-1α in the retina under hypoxic and hyperoxic conditions. B: Increased expression of Hif-1α in the RPE at hypoxia or hyperoxic conditions C: Up-regulation of TRX and HO-1 in the RPE exposed to light.