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Effect of cotransfection of mutant clones on the LPV susceptibility of WT virus
| Mutant clone cotransfected | IC50 for WT pNL4-3-Rluc of LPV (μM) at indicated % of mutant DNA cotransfected
|
|
|---|---|---|
| 50% | 67% | |
| 4 | 0.011 | 0.021 |
| 8 | 0.013 | 0.013 |
| 9 | 0.014 | 0.024 |
| 10 | 0.017 | 0.025 |
| pNL4-3-Fluc-x (WT) | 0.014 | 0.013 |
