TABLE 4.
Macrolide and clindamycin susceptibilities and their genotypic determinants
| Isolate no. | Identification | MIC (μg/ml)
|
Presence of determinant:
|
||||
|---|---|---|---|---|---|---|---|
| Erythromycin | Clindamycin | erm(A) | erm(B) | mef(A) | tet(M) | ||
| 1 | G. elegans | >64 | >64 | − | + | + | + |
| 2 | G. adiacens | >64 | >64 | − | + | − | + |
| 3 | G. adiacens | 8a | ≥256a | − | + | − | + |
| 4 | G. adiacens | 8 | 0.25 | − | − | + | NDb |
| 5 | G. adiacens | 16 | 0.019 | − | − | + | ND |
| 6 | G. adiacens | 16 | 0.125 | − | − | + | ND |
| 7 | A. defectiva | 16 | 0.125 | − | − | + | ND |
| 8 | A. defectiva | 2 | 0.06 | − | − | + | ND |
| Susceptible isolates (9-15) | G. adiacens (n = 2) | 0.125 and <0.03 | 0.25 and 0.125 | − | − | − | ND |
| A. defectiva (n = 3) | ≤0.125 | ≤0.125 | − | − | − | ND | |
| G. elegans (n = 2) | ≤0.094a | ≤0.064a | − | − | − | ND | |
a
Etest was used when poor growth in broth precluded assessment by microbroth dilution method.
b
ND, not done.