TABLE 1.
Parameter | Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | Patient 6 |
---|---|---|---|---|---|---|
Age (yr)/sex | 34/M | 47/M | 25/M | 34/M | 28/M | 15/F |
Date of symptom onset (day/mo/yr) | 10/11/2002 | 7/4/2003 | 20/4/2003 | 4/5/2003 | 3/8/2003 | 28/9/2003 |
Place of contamination | Paris | Paris | Paris | Paris | Cape Verde | Morocco |
Risk factor | MSM HIV | MSM HIV | MSM HIV | Unknown | International travel | International travel |
Date of serum sampling (day/mo/yr) | 14/11/2002 | 15/4/2003 | 22/4/2003 | 8/5/2003 | 7/8/2003 | 8/10/2003 |
Date of saliva sampling (day/mo/yr) | 21/11/2002 | 17/4/2003 | 25/4/2003 | 9/5/2003 | 8/5/2003 | 8/10/2003 |
ALT (IU/ml) | 632 | 238 | 2,800 | 6,150 | 3,600 | 4,000 |
Serum VP1/2A RNA | + | + | + | + | + | + |
Serum RNA quantification | 4.9 × 106 | 7.3 × 103 | 2.3 × 107 | 3.6 × 105 | 2.2 × 104 | 4.1 × 104 |
Saliva VP1/2A RNA | + | − | + | + | + | + |
Saliva RNA quantification | 9.3 × 102 | / | 1.9 × 104 | 3.5 × 103 | <6.0 × 102 | 1.1 × 103 |
Copies in serum/copies in saliva (log units) | 2.25 | / | 1.72 | 1.29 | >1.6 | 1.52 |
HAV genotype | IA | IA | IA | IA | IB | IA |
M, male; F, female; ALT, alanine aminotransferase level; MSM, men having sex with men; +, presence; −, absence; /, not performed.