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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Biochim Biophys Acta. 2016 Nov 4;1863(1):298–309. doi: 10.1016/j.bbadis.2016.11.006

Figure 4.

Figure 4

Effects of bFGF on collagen pad contraction and fibroblast gene expression. A-B. bFGF enhanced contraction of fibroblast-populated collagen pads (scalebar=5mm). C. bFGF stimulation reduced α-SMA expression by cardiac fibroblasts. bFGF attenuated collagen I (D) and III (E) synthesis. F. bFGF reduced fibroblast MMP2 expression. G. bFGF did not affect MMP3 synthesis (G), but significantly decreased MMP8 expression by cardiac fibroblasts. I. bFGF accentuated TIMP1 expression (**p<0.01, n=8–14/group).