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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Endod. 2016 Nov 12;43(1):109–115. doi: 10.1016/j.joen.2016.09.007

Figure 3. The dKO mice developed delayed molar eruption (right panels).

Figure 3

a) X-ray images showed a lack of molar eruption in the dKO mice compared to the age-matched controls, in which both 1st and 2nd molars are fully erupted; b) TRAP stain images showed more positive osteoclasts (black arrow) in CTR mice than in dKO mice, with a statistical difference between these two groups (n=4, *; P<0.05); and c) DMP1 immunostain images displayed a major defect in alveolar bone formation in the dKO mice.