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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: J Endod. 2016 Nov 12;43(1):109–115. doi: 10.1016/j.joen.2016.09.007

Figure 4. Depictions of a critical role for BMP1/TLL1 during postnatal tooth root formation.

Figure 4

Here we propose that the closely related proteinases BMP1/TLL1 are required for maintaining matrix homeostasis during postnatal tooth development. Ablation of these two proteinases led to shortened roots and severe deficits in dentin mineralization, and exhibiting of a DGI-like phenotype.