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. Author manuscript; available in PMC: 2018 Jan 15.
Published in final edited form as: Int J Cardiol. 2016 Oct 29;227:668–673. doi: 10.1016/j.ijcard.2016.10.078

Figure 2. Absence of detrimental effects on systolic SR Ca2+ handling and inhibition of spontaneous Ca2+ waves (SCaWs) by EL9.

Figure 2

(A) Representative recordings of paced Ca2+ transients in WT or R176Q/+ myocytes using 1-Hz field stimulation, in the presence of vehicle or EL9. (B) Summary data showing that EL9 did not alter the Ca2+ transient amplitude in ventricular myocytes from WT and R176Q/+ mice. (C) Representative recordings of SCaWs in R176Q/+ myocytes in the presence of vehicle, flecainide (600 nmol/L), or EL9 (500 nmol/L). (D) Incidence of SCaWs in R176Q/+ myocytes. *P<0.05, **P<0.01.