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. Author manuscript; available in PMC: 2017 Mar 21.
Published in final edited form as: Nature. 2016 Sep 21;538(7624):238–242. doi: 10.1038/nature19792

ED10. Proposed xOoA model.

ED10

A subway map figure illustrating, as suggested by the novel results presented here, a model of an early, extinct Out-of-Africa (xOoA) signature in the genomes of Sahul populations at their arrival in the region. Given the overall small genomic contribution of this event to the genomes of modern Sahul individuals, we could not determine whether the documented Denisova admixture (question marks) and putative multiple Neanderthal admixtures took place along this extinct OoA. We also speculate (question mark) people who migrated along the xOoA route may have left a trace in the genomes of the Altai Neanderthal as reported by Kuhlwilm and colleagues12.