Table 3.
Clinical Characteristics and Relationship with Distant Metastases in Patients undergoing R0 resection.
| No Metastases | Metastases | P value | |
|---|---|---|---|
|
| |||
| Mutation status (n=63) | |||
| Sporadic | 28 | 1 | |
| SDHB mutation | 17 | 17 | P<0.001 |
|
| |||
| Mean Tumor Size (cm) (n=53) | 3.7 ± 0.3 | 7.7 ± 0.9 | P<0.001 |
|
| |||
| Functionality (n=48) | |||
| Nonfunctioning | 5 | 3 | |
| Metanephrine* | 3 | 0 | |
| Normetanephrine* | 11 | 5 | |
| Dopamine* | 3 | 3 | |
| Combination^ | 10 | 5 | P=0.77 |
|
| |||
| Tumor type (n=52)# | |||
| Pheochromocytoma | 30 | 2 | |
| Paraganglioma | 12 | 8 | P=0.004 |
|
| |||
| Approach (n=52) | |||
| Open | 7 | 13 | |
| Laparoscopic | 31 | 1 | P<0.001 |
|
| |||
| Ki67% (n=40) | |||
| Under 1% | 25 | 3 | |
| 1 – 3% | 6 | 1 | |
| Over 3% | 3 | 2 | P=0.22 |
|
| |||
| Mitotic Index (n=38) | |||
| 0 | 15 | 1 | |
| 1 | 10 | 3 | |
| ≥2 | 7 | 2 | P=.28 |
Data are presented as frequencies and percentages unless otherwise stated.
§
Mean tumor diameter in cm ± SD.
*
Number of patients with biochemical value above normal range.
^
Combination of biochemical secretion.
#
Based on histology and anatomic location at the time of the operation or on anatomic imaging studies.