Table 2.
The spatial density (“spike frequency analysis”) and spatiotemporal propagation (“recruitment latency analysis”) of interictal spike discharges were examined.
Patient (n = 18) | Spike frequency analysis |
Recruitment latency analysis |
|||
---|---|---|---|---|---|
Spike density (spikes/chan/min) | Moran Index | Total sequences (n) | Sequence frequency (seqs/min) | Moran Index | |
Pt 01 | 0.377 | 0.527 | 135 | 0.1283 | 0.501 |
Pt 02 | 2.956 | 0.403 | 2,224 | 6.5745 | 0.307 |
Pt 03 | 6.578 | 0.284 | 739 | 4.8125 | 0.282 |
Pt 04 | 2.386 | 0.589 | 774 | 1.7361 | 0.338 |
Pt 05 | 5.085 | 0.427 | 1,018 | 5.1247 | 0.411 |
Pt 06 | 1.359 | 0.493 | 806 | 1.1831 | 0.349 |
Pt 07 | 1.808 | 0.153 | 993 | 2.2260 | 0.182 |
Pt 08 | 1.716 | 0.417 | 1,076 | 2.3636 | 0.178 |
Pt 09 | 4.552 | 0.488 | 1,845 | 9.7421 | 0.451 |
Pt 10 | 2.739 | 0.304 | 1,680 | 4.2328 | 0.832 |
Pt 11 | 10.685 | 0.705 | 2,292 | 26.4504 | 0.368 |
Pt 12 | 2.154 | 0.300 | 2,652 | 6.2840 | 0.411 |
Pt 13 | 0.992 | 0.335 | 916 | 0.8907 | 0.272 |
Pt 14 | 1.206 | 0.525 | 1,072 | 1.3445 | 0.151 |
Pt 15 | 0.391 | 0.203 | 1,323 | 0.5997 | 0.425 |
Pt 16 | 0.904 | 0.465 | 1,895 | 1.2681 | 0.437 |
Pt 17 | 1.020 | 0.218 | 923 | 1.0076 | 0.316 |
Pt 18 | 1.700 | 0.324 | 1,240 | 1.7710 | 0.283 |
Sz-Free | 3.05 ± 3.35 | 0.407 ± 0.161 | 1,372.3 ± 643.8 | 5.59 ± 8.39 | 0.447 ± 0.160 |
Sz-Persist | 2.35 ± 1.70 | 0.389 ± 0.136 | 1,250.2 ± 692.7 | 3.05 ± 2.23 | 0.275 ± 0.088 |
p-Value | 0.730 | 0.863 | 0.340 | 0.863 | 0.003 |
Patient-wise results from the two spike analyses are displayed. Patients exhibited highly variable spike density (spikes per channel per minute) and sequence frequency (sequences per minute), though differences between groups were not observed. Sz-Free patients exhibit significantly more organized recruitment latency maps (Moran Index) than Sz-Persist patients (Wilcoxon rank sum test, p = 0.003).