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. 2016 Dec 19;7:229. doi: 10.3389/fneur.2016.00229

Table 2.

The spatial density (“spike frequency analysis”) and spatiotemporal propagation (“recruitment latency analysis”) of interictal spike discharges were examined.

Patient (n = 18) Spike frequency analysis
Recruitment latency analysis
Spike density (spikes/chan/min) Moran Index Total sequences (n) Sequence frequency (seqs/min) Moran Index
Pt 01 0.377 0.527 135 0.1283 0.501
Pt 02 2.956 0.403 2,224 6.5745 0.307
Pt 03 6.578 0.284 739 4.8125 0.282
Pt 04 2.386 0.589 774 1.7361 0.338
Pt 05 5.085 0.427 1,018 5.1247 0.411
Pt 06 1.359 0.493 806 1.1831 0.349
Pt 07 1.808 0.153 993 2.2260 0.182
Pt 08 1.716 0.417 1,076 2.3636 0.178
Pt 09 4.552 0.488 1,845 9.7421 0.451
Pt 10 2.739 0.304 1,680 4.2328 0.832
Pt 11 10.685 0.705 2,292 26.4504 0.368
Pt 12 2.154 0.300 2,652 6.2840 0.411
Pt 13 0.992 0.335 916 0.8907 0.272
Pt 14 1.206 0.525 1,072 1.3445 0.151
Pt 15 0.391 0.203 1,323 0.5997 0.425
Pt 16 0.904 0.465 1,895 1.2681 0.437
Pt 17 1.020 0.218 923 1.0076 0.316
Pt 18 1.700 0.324 1,240 1.7710 0.283
Sz-Free 3.05 ± 3.35 0.407 ± 0.161 1,372.3 ± 643.8 5.59 ± 8.39 0.447 ± 0.160
Sz-Persist 2.35 ± 1.70 0.389 ± 0.136 1,250.2 ± 692.7 3.05 ± 2.23 0.275 ± 0.088
p-Value 0.730 0.863 0.340 0.863 0.003

Patient-wise results from the two spike analyses are displayed. Patients exhibited highly variable spike density (spikes per channel per minute) and sequence frequency (sequences per minute), though differences between groups were not observed. Sz-Free patients exhibit significantly more organized recruitment latency maps (Moran Index) than Sz-Persist patients (Wilcoxon rank sum test, p = 0.003).