Table I.
Characteristics of relatives of men undergoing semen analysis in a study of semen quality and childhood mortality.
| FDR: siblings (n = 79 750) | SDR: aunts/uncles (n = 160 016) | |||
|---|---|---|---|---|
| Fertile controls (n = 40 537) | Men with SA (n = 39 213) | Fertile controls (n = 89 145) | Men with SA (n = 70 871) | |
| Birth year (mean) | 1974 | 1975 | 1948 | 1948 |
| Years of follow-up (mean) | 19.73 | 19.71 | 19.53 | 19.56 |
| All-cause mortality, n (%) | 449 (1.1%) | 406 (1.0%) | 1107 (1.2%) | 772 (1.1%) |
| Congenital malformation-related mortality, n (%) | 65 (0.2%) | 88 (0.2%) | 89 (0.1%) | 61 (0.1%) |
| Cancer-related mortality n (%) | 38 (0.1%) | 34 (0.1%) | 94 (0.1%) | 83 (0.1%) |
| Gender | ||||
| Male, n (%) | 21 264 (52%) | 20 641 (53%) | 46 155 (52%) | 36 642 (52%) |
| Female, n (%) | 19 273 (48%) | 18 572 (47%) | 42 990 (48%) | 34 229 (48%) |
| Relation by semen quality, n (% of men with SA) | ||||
| Sibling of azoospermic | 1588 (4.0%) | 2918 (4.1%) | ||
| Sibling of oligozoospermic | 4131 (10.5%) | 7459 (10.5%) | ||
| Sibling of normozoospermic | 20 202 (51.5%) | 36 543 (51.6%) | ||
| Sibling of hyperzoospermic | 13 292 (33.9%) | 23 951 (33.8%) | ||
FDR: first-degree relative, SDR: second-degree relative, SA: semen analysis.