Schematic organization of the genes encoding the enzymes implicated in the synthesis of glycerophosphoinositol (GPI), CDP-glycerol, or FAD in Aquifex aeolicus and Archaeoglobus fulgidus. Aq_185 and Aq_1368, genes encoding glycerol phosphate cytidylyltransferases; AF1418, gene encoding an FAD synthetase; ADH, aldehyde dehydrogenase; IPCT, inositol phosphate cytidylyltransferase; DIPPS, di-myo-inositol phosphate-phosphate synthase, which also catalyzes the synthesis of GPI-phosphate; AMP-dep. synt, AMP-dependent synthetase; and RibP PPK, ribose phosphate pyrophosphokinase.