Table 4.
The differences in selected parameters of humoral immunity between the study groups.
| Evaluated parameters | Patients with DFUs (n = 68) | Diabetic controls (n = 34) | p value |
|---|---|---|---|
| IgM (g/L) | 1.1 ± 0.82 | 0.94 ± 0.42 | NS |
| IgA (g/L) | 3.56 ± 1.32 | 2.62 ± 1 | p < 0.001 |
| IgG (g/L) | 12.24 ± 3.19 | 10.83 ± 1.69 | p < 0.05 |
| IgG1 (g/L) | 6.85 ± 2.19 | 5.3 ± 1.28 | p < 0.001 |
| IgG2 (g/L) | 4.12 ± 1.85 | 4.12 ± 1.4 | NS |
| IgG3 (g/L) | 0.81 ± 0.51 | 0.62 ± 0.27 | p < 0.05 |
| IgG4 (g/L) | 0.47 ± 0.4 | 0.43 ± 0.38 | NS |
| Deficit of IgG1 (<3,82 g/L) | 2/68 (3%) | 3/34 (9%) | NS |
| Deficit of IgG2 (<2,42 g/L) | 15/68 (22%) | 5/34 (15%) | NS |
| Deficit of IgG3 (<0,22 g/L) | 0 | 0 | NS |
| Deficit of IgG4 (<0,04 g/L) | 3/68 (4%) | 2/34 (6%) | NS |
Data are presented as means ± SD; patients with DFUs (diabetic foot ulcers; n = 68); age, sex, and type of diabetes matched diabetic controls (n = 34); Ig: immunoglobulin; NS: nonsignificant; p value of significance between patients with DFUs and diabetic controls determined using t-test or Mann–Whitney test.