Table 1.
Summary of the changes observed in young and old animals after 28 days of GH and Mel administration. The table shows the changes in body weight (BW), in distance run, in immobility, and in movement, as directly recorded in the radial maze test. The table also shows the derived variables, average speed of movement, and energetic expenditure. Please note that 100% would mean no change, while changes over and under 100% mean increases and decreases, respectively.
| Compared groups | Δ in BW | Δ in distance run | Δ in immobility time | Δ in movement time | Δ in average speed | Δ in energy spent |
|---|---|---|---|---|---|---|
| Young vehicle/young GH (effects of GH in young) | 129% | 65% | 87% | 29% | 233% | 720% |
| Old vehicle/old GH (effects of GH in old) | 112% | 81% | 64% | 64% | 121% | 167% |
| Young GH/old GH (interaction age, GH) | 155% | 163% | 130% | 456% | 81% | 19% |
|
| ||||||
| Young vehicle/young Mel (effects of Mel in young) | 112% | 84% | 79% | 186% | 46% | 26% |
| Old vehicle/old Mel (effects of GH in old) | 108% | 73% | 41% | 145% | 49% | 25% |
| Young Mel/old Mel (interaction age, Mel) | 174% | 114% | 92% | 159% | 71% | 75% |
|
| ||||||
| Young Mel/young GH (comparing the effects of MEL and GH in young) | 86% | 129% | 110% | 652% | 20% | 3.7% |
| Old Mel/old GH (comparing the effects MEL and GH in old) | 96% | 90% | 155% | 228% | 40% | 15% |