FIG 2.

Displacement of cell nuclei during dysregulated syncytium formation in VZV-infected cells. (A to C) The displacement (A), mean velocity (B), and maximum velocity (C) of nuclei (n = 200) were calculated using the TrackMate plugin of FiJi. Error bars show standard error of the mean. (D and E) Quantification of plaque sizes (n = 50) and immunohistochemistry of representative plaques at 3 days postinfection (dpi) (size is given in the bottom right hand corners) in LifeAct-tGFP melanoma cells infected with pOka or gB[Y881F]. A two-tailed t test was used to calculate significant differences between pOka and gB[Y881F] (****, P < 0.001.