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Interaction analysis of EAV nsp11 H141A and K170A mutants. Shown are protomers in an asymmetric unit of the EAV nsp11 K170A (A) and H141A (E) mutants and interfaces of the EAV nsp11 K170A (B and C) and H141A (F to H) mutants. Key residues involved in the interaction are shown. Similar interfaces were found in the aligned EAV nsp11 K170A and H141A mutant structures (D); for example, the interface in panel G is similar to that in panel C.
