Table 1.
Overview of Spectral Analysis methods.
| Full Name | Exponential Spectral Analysis | Rank-shaping spectral analysis | Spectral analysis with iterative filter | Nonlinear spectral analysis |
|---|---|---|---|---|
| Description | ||||
| Short name | ESA | RS | SAIF | NLSA |
| Type of tracer kinetics | Any | Reversible tracers only | Irreversible tracers only | Any |
| Main parameters of interest | V T/K i, V b, K 1 | V T | K i, V b, K 1 | V T/K i, V b, K 1 |
| Required settings | Grid of components | Grid of components SNR | Grid of components Filter passband | None |
|
| ||||
| Outputs | ||||
| Data fit | ✓ | ✓ | ✓ | ✓ |
| Kinetic spectrum | ✓ | — | ✓ | ✓ |
| ROI analysis | ✓ | — | ✓ | ✓ |
| VOXEL analysis | — | ✓ | ✓ | — |
V T: distribution volume; K i: trapping rate constant; V b: blood volume; K 1: weighted average influx rate constant; SNR: signal-to-noise ratio.